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Glowing DNA research

Christine Cardin, Professor Crystallography
Professor Christine Cardin and her colleagues work with molecules that have a similar property to glow-in-the-dark, except they glow when binding to DNA instead.

Christine is a the world leader in the structural study of these compounds bound to DNA.

"I'm interested in how compounds that are important to drug discovery bind to DNA. The molecules may have important therapeutic uses, or be useful for diagnostics of cancer, so people were trying to develop new ones, but didn't know how they bound to DNA.


"The beauty of the X-ray crystallography technique is that it shows you exactly what your molecule looks like. The minute I saw that, I loved it, and was hooked on it."

The "light-switch" complex

Watch our video showing the symmetrical intercalation of a ruthenium "light-switch" complex.

Researching with students

Chemistry undergraduates and pos